Comparative characteristics of nitroglycerin, sodium nitropracide and phenol mine effect on hemodynamic

The effects of nitroglycerin, sodium nitropraaside and phenol mine infusion on hemodynamic, regional contraction and dogs were studied in the degree of ischemic myocardial damage in coronary myocardial infarction. With the intravenous administration of each of the three drugs, there is more or less obvious increase in heart rate.  [pic-source](https://pixabay.com) The biggest increase in rhythm was the cause of FA, the smallest - nag. With the administration of NPN, and with the introduction of FA, some of the lower blood pressure decreased. NG reduced systolic blood pressure compared to diastolic, nitro acid and phenol mine. NPN and FA caused a significant reduction in diastolic blood pressure. All three drugs have significantly reduced the end diastolic pressure in the left ventricle. On average, after the introduction of each medication, there was a decrease in cardiovascular production in all groups and reduction in total peripheral vascular resistance. However, in some dogs, in some cases, these indicators did not change; sometimes the volume of minutes was also seen. In 82% of studies, partial and in some cases, the complete restoration of the contraction of the ischemic regions of myocardium was mentioned in the effect of nag. In other cases, its introduction did not either affect regional contraction or spoiled it. The impact of NNP on the contractual function of ischemic myocardium was not very different from the effect of NG. FAs cause a significant improvement in the regional myocardial contraction in the ischemic region in all cases. In some cases, after the administration of the FA, the signs of regional contraction were not only higher than the values received after coronary obstruction, but initial values were also. There were no significant differences in the effect of NG and NPN on the intact sections of the left ventricle. Both drugs reduced compensative myocardial hyperkinesias, resulting in increased systolic hemorrhage of the intact wall area. After the introduction of NG and NPN in 30.8 and 25% cases respectively, ECG showed a decrease in the increase of ST segment to 53.8 and 37.5%, 15.4 and 37.5% in cases of significant changes in this indicator was not celebrated. No relation was found between the change in ST segment and the change in heart rate, the effect of NG and NPN in BP change. After the introduction of FA in all cases, the increase in the height of the ST segment was seen at an average of 44%. Explanation in experiment is very relevant, with the use of modern and accurate methods of research on the specialty of NG, NNP and FA in local myocardial ischemia. The work was done at a high functioning level, it achieved interesting results. As is known, the above preparation has a complex and diverse effect on the cardiovascular system. This difference was also seen in response to cardiac reaction with local ischemia for the administration of drugs. Meditation is ready for a significant increase in stroke volume, minute quantity, and heart rate, DP / DT / P and DP / DT under FA's action. The last indicator, reduced under the action of DP / DT, NNP and NG. The authors discussed this effect in detail with reference to literature data on the effect of an adrenergic receptor blockade on the heart. However, the fact that FA stops a co-adrenergic myocardial receptor to a large extent, which is responsible for the rupture of the norepeniferen, is ignored. This can be the reason for an increase in the contraction of the heart. At the same time, the authors believe that FA does not reduce the endocardocardial perfusion and does not increase the area of developing myocardial infarction.